928038-49-7

Basic information

• Product Name: 1,1-Cyclopropanedicarboxamide, N-[4-[(6-amino-4-pyrimidinyl)oxy]-2,5-difluorophenyl]-N'-(4-fluorophenyl) -
• CAS NO: 928038-49-7
• Molecular Formula: C21H16F3N5O3
• Molecular Weight: 443.385
• Mol File: 928038-49-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-Cyclopropanedicarboxamide, N-[4-[(6-amino-4-pyrimidinyl)oxy]-2,5-difluorophenyl]-N'-(4-fluorophenyl) -(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Cyclopropanedicarboxamide, N-[4-[(6-amino-4-pyrimidinyl)oxy]-2,5-difluorophenyl]-N'-(4-fluorophenyl) -(928038-49-7)
• EPA Substance Registry System: 1,1-Cyclopropanedicarboxamide, N-[4-[(6-amino-4-pyrimidinyl)oxy]-2,5-difluorophenyl]-N'-(4-fluorophenyl) -(928038-49-7)

Safety Data

• Hazardous Substances Data: 928038-49-7(Hazardous Substances Data)

Upstream product

• 2105-61-5 1,2,4-trifluoro-5-nitrobenzene 
• 928038-46-4 Benzyl [4-(4-aminopyrimidin-6-yloxy)-2,5-difluorophenyl]carbamate 
• 928038-47-5 Benzyl [4-(4-azidopyrimidin-6-yloxy)-2,5-difluorophenyl]carbamate 
• 928038-45-3 benzyl [4-(4-chloropyrimidin-6-yloxy)-2,5-difluorophenyl]carbamate 
• 868736-12-3 1-(benzyloxy)-2,5-difluoro-4-nitrobenzene 
• 120103-19-7 4-amino-2,5-difluorophenol 
• 928038-48-6 4-amino-6-(4-amino-2,5-difluorophenoxy)pyrimidine 

Relevant articles and documents

NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3)

A compound represented by the following formula, a salt thereof or a hydrate of the foregoing has an excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity and cancer metastasis inhibitory activity. [R1 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; R2 and R3 represent hydrogen; R4, R5, R6, and R7 may be the same or different and each represents hydrogen, halogen, C1-6 alkyl or the like; R8 represents hydrogen or the like; R9 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; n represents an integer of 1 or 2; X represents -CH=, nitrogen or the like.]