92847-34-2Relevant academic research and scientific papers
PYRAZOLOPYRIMIDINE DERIVATIVES
-
Page/Page column 126, (2017/11/10)
The present invention covers Pyrazolopyrimidine compounds of general formula (I), in which n, o, X, Y, R, Q, R1, R2, R3 and R4 are as defined herein, methods of preparing said compounds, intermediate compounds u
Phosphine-catalyzed regioselective Michael addition to allenoates
Gandi, Vasudeva Rao,Lu, Yixin
supporting information, p. 16188 - 16190 (2015/11/10)
The first phosphine catalysed Michael addition of arylcyanoacetates to allenoates has been developed, and the β-selective products with a quaternary center were obtained in excellent yields. This unusual regioselectivity may open new opportunities to acce
OCTAHYDROPYRROLO [3, 4-C] PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS
-
Page/Page column 65, (2008/06/13)
Chemokine receptor antagonists, in particular, 3,7-diazabicyclo [3.3.0] octane compounds according to formula (I) wherein R1-R3 and Ar are as defined herein are antagonists of chemokine CCR5 receptors which are useful for treating or preventing an human immunodeficiency virus (HIV) infection, or treating AIDS or ARC. The invention further provides methods for treating diseases that are alleviated with CCR5 antagonists. The invention includes pharmaceutical compositions and methods of using the compounds for the treatment of these diseases. The invention further includes processes for the preparation of compounds according to formula (I).
AROMATIC NUCLEOPHILIC SUBSTITUTION ON η6-Cr(CO)3-COMPLEXED HALOGENOARENES: ARYLATION OF SECONDARY CARBANIONS
Baldoli, Clara,Buttero, Paola Del,Licandro, Emanuela,Maiorana, Stefano
, p. 409 - 414 (2007/10/02)
The paper deals with the aromatic nucleophilic substitution on η6-Cr(CO)3-complexed fluorobenzene and ortho-, meta-, and para-dichlorobenzenes with stabilized carbanions, both under phase-transfer conditions (PTC) and in DMSO solution.In the case of the η6-Cr(CO)3-complexed ortho-, meta-, and para-dichlorobenzenes only one chlorine atom is replaced by the carbanions.
