92850-45-8

Upstream product

• 100-42-5 styrene 
• 104-94-9 4-methoxy-aniline 
• 50916-21-7 N-(4-methoxyphenyl)-2-phenylacetamide 

Downstream Products

• 113742-55-5 4-Methoxy-N-(2-phenylethenylidene)aniline 
• 137242-88-7 trans-1-(4-methoxyphenyl)-3-phenoxy-4-phenylmethyl-4-methylthio-azetidin-2-one 
• 137242-92-3 cis-N-(4-methoxyphenyl)-3-phenoxy-4-methylphenyl-azetidin-2-one 
• 130369-80-1 trans-1-(4-methoxyphenyl)-3-phthalimido-4-phenylmethyl-4-methylthio-azetidin-2-one 
• 130650-37-2 S-methyl N-(4-methoxyphenyl)-phenylacetthioimidate 

Relevant academic research and scientific papers

Base-Controlled Three Component Reactions of Amines, Elemental Sulfur, and Styrenes: Synthesis of Thioamides under Metal-Free Conditions

Three component reactions of olefins, amines, and sulfur were studied. Thioamidation of styrenes is base-controlled, and 2-phenylethanethioamides and benzothioamides were obtained selectively in the presence of two different bases. This protocol offers a simple and efficient procedure for the synthesis of thioamides.

Selective reduction of carbonyl groups in the presence of low-valent titanium reagents

The chemoselective reduction of several structurally diverse compounds containing carbonyl groups was achieved in the presence of low-valent titanium reagents. This novel synthetic method provides easy access to highly selective reduction of carbonyl groups, and possesses several advantages including one-step procedure, convenient manipulation, good to excellent yields, and short reaction times.

A convenient synthesis of β-lactams from alkylthioimidates

Stereoselective syntheses of trans-3,4,4-substituted-azetidin-2-ones from alkylthioimidates are described. Reduction of these compounds gave stereoselectively cis-4-alkyl-azetidin-2-ones which could be useful intermediates for preparation of biologically