92855-13-5Relevant academic research and scientific papers
Conformational analysis of N-aryl-N-(2-azulenyl)acetamides
Ito, Ai,Amaki, Takamasa,Ishii, Ayako,Fukuda, Kazuo,Yamasaki, Ryu,Okamoto, Iwao
, p. 3994 - 3998 (2018)
Aromatic amides bearing 2-azulenyl group on the amide nitrogen were synthesized and their structures were investigated. The π-electron density of the N-aryl group was found to influence the cis-trans conformational preferences of these compounds in solution. X-ray crystallography revealed that the plane of the 2-azulenyl ring has a strong tendency to lie coplanar with the amide plane when the azulene group is located on the same side as the amide oxygen atom.
Synthesis of 2-aminoazulene derivatives. Nucleophilic and palladium-catalyzed amination of 2-substituted azulene
Yokoyama, Ryuji,Ito, Shunji,Okujima, Tetsuo,Kubo, Takahiro,Yasunami, Masafumi,Tajiri, Akio,Morita, Noboru
, p. 8191 - 8198 (2007/10/03)
Amination of 2-substituted azulene was carefully examined using several types of amines, and the scope and limitation of substrates and reagents in these direct nucleophilic aminations were found. The synthesis of 2-aminoazulenes was successfully achieved by the reaction of 2-bromoazulene with several amines via palladium-catalyzed amination.
