36044-40-3

Upstream product

• 3806-02-8 diethyl 2-aminoazulene-1,3-dicarboxylate 
• 3839-48-3 2-chlorotropone 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 36044-31-2 2-chloroazulene 
• 63965-64-0 diethyl 4-(phenylethynyl)azulene-1,3-dicarboxylate 
• 75628-82-9 diethyl 6-(phenylethynyl)azulene-1,3-dicarboxylate 
• 52457-19-9 diethyl 2-chloro-4-phenylazulene-1,3-dicarboxylate 
• 52457-21-3 Diethyl 2-chloro-6-phenylazulene-1,3-dicarboxylate 
• 50469-71-1 2-amino-6-bromoazulene-1,3-dicarboxylic acid diethyl ester 
• 92855-13-5 N-(2-azulenyl)aniline 
• 94256-67-4 2-Anilino-azulen-1-carbonsaeure-aethylester 
• 95166-91-9 6-Brom-2-anilino-azulen-1.3-dicarbonsaeure-diethylester 
• 7175-71-5 azulene-2-carboxylic acid 
• 36044-41-4 2-iodoazulene 
• 769-86-8 2-methylazulene 
• 82894-18-6 2,2'-biazulene-1,1'-dicarboxylic acid 
• 133413-87-3 diethyl 2-styryl-1,3-azulenedicarboxylate 

Relevant academic research and scientific papers

Synthesis of 2- and 6-thienylazulenes by palladium-catalyzed direct arylation of 2- and 6-haloazulenes with thiophene derivatives

Preparation of 2- and 6-thienylazulene derivatives was established by the palladium-catalyzed direct cross-coupling reaction of 2- and 6-haloazulenes with the corresponding thiophene derivatives in good yield. Several thienylazulene derivatives were also used in the reaction with 2-chloroazulene derivatives in the presence of the palladium-catalyst to afford the thiophene derivatives with two azulene functions in good yield.

Arylation of diethyl 2-chloroazulene-1,3-dicarboxylate with Grignard reagent

Reaction of diethyl 2-chloroazulene-1,3-dicarboxylate (2) with phenyl magnesium bromide, followed by oxidation with o-chloranil, gave diethyl 2-chloro-4-phenylazulene-1,3-dicarboxylate (3), diethyl 2-chloro-5-phenylazulene-1,3-dicarboxylate (4) and diethy