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928653-75-2

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928653-75-2 Usage

Description

3-Iodo-4-methoxy-1H-pyrrolo[2,3-b]pyridine, commonly referred to as IMPY, is a heterocyclic compound characterized by its molecular formula C9H7IN2O. As a derivative of pyrrolo[2,3-b]pyridine, IMPY distinguishes itself as a potent and selective ligand for the sigma-1 receptor. This receptor is implicated in numerous neurological processes, making IMPY a significant compound in the realm of medicinal chemistry and neuroscience.

Uses

Used in Pharmaceutical Research:
3-Iodo-4-methoxy-1H-pyrrolo[2,3-b]pyridine is utilized as a research tool for studying the sigma-1 receptor, which is involved in various neurological functions. Its selectivity for this receptor makes it valuable in exploring the receptor's role in neurodegenerative diseases and potential drug development.
Used in Neurodegenerative Disease Treatment:
In the field of neurology, 3-Iodo-4-methoxy-1H-pyrrolo[2,3-b]pyridine is considered for its potential therapeutic effects in treating neurodegenerative conditions such as Alzheimer's and Parkinson's disease. Its interaction with the sigma-1 receptor suggests a possible avenue for symptom management or disease modification.
Used in Oncology Research:
3-Iodo-4-methoxy-1H-pyrrolo[2,3-b]pyridine is also being investigated for its potential use in cancer treatment. Its role as a sigma-1 receptor ligand may offer insights into cancer biology and the development of novel therapeutic strategies targeting this receptor in oncological applications.
Used in Psychiatric Disorder Research:
In the psychiatric field, 3-Iodo-4-methoxy-1H-pyrrolo[2,3-b]pyridine serves as a compound of interest for studying the sigma-1 receptor's involvement in psychiatric disorders. Understanding its interaction with the receptor may pave the way for new treatments or therapeutic approaches for mental health conditions.
Overall, 3-Iodo-4-methoxy-1H-pyrrolo[2,3-b]pyridine, or IMPY, is a versatile compound with applications spanning across different areas of medical and scientific research, particularly in the realms of neurology, oncology, and psychiatry. Its role as a selective sigma-1 receptor ligand positions it as a key player in the development of future therapeutics and a deepening understanding of receptor biology.

Check Digit Verification of cas no

The CAS Registry Mumber 928653-75-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,8,6,5 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 928653-75:
(8*9)+(7*2)+(6*8)+(5*6)+(4*5)+(3*3)+(2*7)+(1*5)=212
212 % 10 = 2
So 928653-75-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H7IN2O/c1-12-6-2-3-10-8-7(6)5(9)4-11-8/h2-4H,1H3,(H,10,11)

928653-75-2 Well-known Company Product Price

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  • Aldrich

  • (ADE000911)  3-Iodo-4-methoxy-1H-pyrrolo[2,3-b]pyridine  AldrichCPR

  • 928653-75-2

  • ADE000911-1G

  • 7,411.95CNY

  • Detail

928653-75-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Iodo-4-methoxy-1H-pyrrolo[2,3-b]pyridine

1.2 Other means of identification

Product number -
Other names 3-IODO-4-METHOXY-7-AZAINDOLE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:928653-75-2 SDS

928653-75-2Relevant articles and documents

Sequentially Catalyzed Three-Component Masuda-Suzuki-Sonogashira Synthesis of Fluorescent 2-Alkynyl-4-(7-azaindol-3-yl)pyrimidines: Three Palladium-Catalyzed Processes in a One-Pot Fashion

Drieβen, Daniel,Biesen, Lukas,Müller, Thomas J. J.

supporting information, p. 491 - 496 (2021/03/09)

The Masuda-Suzuki-Sonogashira sequence efficiently unites, in a one-pot fashion, a borylation, an arylation, and an alkynylation in the sense of a sequentially Pd-catalyzed three-component reaction to give fluorescent 2-alkynyl-4-(7-azaindol-3-yl) pyrimid

3-(1,2,3-Triazol-4-yl) pyrrolo [2,3-b] pyridine derivatives

-

Page/Page column 17, (2012/03/12)

Compounds of the formula (I), in which R1, R2 and R3 have the meanings indicated in claim (1), are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumours.

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