928655-45-2

Basic information

• Product Name: Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2S,3S)-, compd. with (5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin -5-yl 4-methyl-1-piperazinecarboxylate (1:1)
• CAS NO: 928655-45-2
• Molecular Formula: C20H18O8.C17H17ClN6O3
• Molecular Weight: 775.171
• Mol File: 928655-45-2.mol

Chemical Properties

• CAS DataBase Reference: Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2S,3S)-, compd. with (5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin -5-yl 4-methyl-1-piperazinecarboxylate (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2S,3S)-, compd. with (5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin -5-yl 4-methyl-1-piperazinecarboxylate (1:1)(928655-45-2)
• EPA Substance Registry System: Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2S,3S)-, compd. with (5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin -5-yl 4-methyl-1-piperazinecarboxylate (1:1)(928655-45-2)

Safety Data

• Hazardous Substances Data: 928655-45-2(Hazardous Substances Data)

Upstream product

• 32634-68-7 (2S,3S)-di-4-toluoyltartaric acid 
• 43200-80-2 zopiclon 

Downstream Products

• 138729-47-2 eszopiclone 

Relevant articles and documents

IMPROVED PROCESS FOR THE PREPARATION OF AN OPTICALLY ACTIVE 5H-PYRROLO [3,4-B] PYRAZINE DERIVATIVE

A substantially pure dextrorotatory isomer of zopiclone or a pharmaceutically acceptable salt thereof and crystalline forms thereof are provided. Also provided is a process for its preparation and pharmaceutical compositions containing same.

ESZOPICLONE PROCESS

Eszopiclone is prepared by reacting zopiclone with an enatiomerically pure di-p-toluoyl tartaric acid, recovering a solid salt, and reacting a solid salt with a base. Zopiclone is prepared by reacting 6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrr