928756-86-9Relevant academic research and scientific papers
Synthesis of vinyl sulfides via hydrothiolation of alkynes using Al2O3/KF under solvent-free conditions
Silva, Márcio S.,Lara, Renata G.,Marczewski, Júnior M.,Jacob, Raquel G.,Lenard?o, Eder J.,Perin, Gelson
, p. 1927 - 1930 (2008)
We present here a clean, solvent-free hydrothiolation of alkynes using solid supported catalyst (Al2O3/KF). This efficient and improved method selectively furnishes the corresponding anti-Markovnikov vinyl sulfides in good to excellent yields. The method is applicable for aliphatic and aromatic thiols and the catalytic system can be re-used up to two times without previous treatment and with comparable activity.
