928790-01-6Relevant articles and documents
Organocatalysis with a fluorous tag: Asymmetric reduction of imines with trichlorosilane catalyzed by amino acid-derived formamides
Malkov, Andrei V.,Figlus, Marek,Stoncius, Sigitas,Kocovsky, Pavel
, p. 1315 - 1325 (2007/10/03)
(Chemical Equation Presented) Asymmetric reduction of ketimines 1 with trichlorosilane can be catalyzed by N-methylvaline-derived Lewis-basic formamides 3a-d with high enantioselectivity (≤95% ee) and low catalyst loading (1-5 mol %) at room temperature i