928839-68-3Relevant articles and documents
Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-based design and synthesis of new templates
Malancona, Savina,Donghi, Monica,Ferrara, Marco,Martin Hernando, Josè I.,Pompei, Marco,Pesci, Silvia,Ontoria, Jesus M.,Koch, Uwe,Rowley, Michael,Summa, Vincenzo
experimental part, p. 2836 - 2848 (2010/07/04)
Chronic hepatitis C virus (HCV) infections are a significant medical problem worldwide. The NS5B Polymerase of HCV plays a central role in virus replication and is a prime target for the discovery of new treatment options. We recently disclosed 1H-benzo[d
QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS
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Page/Page column 37, (2010/11/26)
The present invention relates to the use of quinazoline derivatives of formula (I) wherein A, B, R1, R2, R3 and R4 are defined herein, and pharmaceutically acceptable salts thereof, for the treatment or preventi