928853-86-5 Usage
Chemical compound
15-Lipoxygenase Inhibitor 1 is a chemical compound that has been identified as an inhibitor of the enzyme 15-lipoxygenase (15-LOX).
Enzyme inhibition
It inhibits the enzyme 15-lipoxygenase (15-LOX), which is involved in the biosynthesis of lipid mediators implicated in various inflammatory and immune responses.
Modulation of pro-inflammatory lipid mediators
By targeting this specific enzyme, 15-Lipoxygenase Inhibitor 1 has the potential to modulate the production of pro-inflammatory lipid mediators.
Development of novel treatments
It contributes to the development of novel and selective treatments for diseases such as cancer, inflammation, and neurodegenerative disorders.
Further research needed
Further research is needed to fully understand the efficacy and safety profile of 15-Lipoxygenase Inhibitor 1 for clinical use.
Check Digit Verification of cas no
The CAS Registry Mumber 928853-86-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,8,8,5 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 928853-86:
(8*9)+(7*2)+(6*8)+(5*8)+(4*5)+(3*3)+(2*8)+(1*6)=225
225 % 10 = 5
So 928853-86-5 is a valid CAS Registry Number.
928853-86-5Relevant academic research and scientific papers
Design and synthesis of pyrimido[4,5-b][1,4]benzothiazine derivatives, as potent 15-lipoxygenase inhibitors
Bakavoli,Nikpour,Rahimizadeh,Saberi,Sadeghian
, p. 2120 - 2126 (2008/02/04)
A group of 2-substituted pyrimido[4,5-b][1,4]benzothiazines were designed, synthesized, and evaluated as potential inhibitors of 15-lipoxygenase (15-LO). Compounds 4d and 4e showed the best IC50 of 15-LO inhibition (IC50 = 18 and 34
