92898-22-1

Upstream product

• 100-42-5 styrene 
• 21544-85-4 2,2-dibromo-5-methyl-1,3-cyclohexanedione 
• 4341-24-6 5-methylcyclohexan-1,3-dione 
• 75326-15-7 (2-bromo-1-phenylethyl)dimethylsulphonium bromide 
• 86396-03-4 (2,6-dioxo-4-methylcyclohexyl)phenyliodonium inner salt 
• 158836-48-7 2-diazo-5-methylcyclohexane-1,3-dione 

Relevant academic research and scientific papers

Acid-Catalyzed Ring-Opening Cyclization of Spirocyclopropanes for the Construction of a 2-Arylbenzofuran Skeleton: Total Synthesis of Cuspidan B

Acid-catalyzed ring-opening cyclization of cyclohexane-1,3-dione-2-spirocyclopropanes under metal-free conditions proceeded smoothly at room temperature to provide 2-aryl-3,5,6,7-tetrahydro-1-benzofuran-4(2H)-ones in excellent yields without the formation

Fused dihydrofurans from the one-pot, three-component reaction of 1,3-cyclohexanedione, iodobenzene diacetate and alkenes

The one-pot, three-component reactions of substituted 1,3- cyclohexanediones, iodobenzene diacetate and alkenes, under photochemical activation, yields fused dihydrofuran derivatives in good yield via the in situ formation of iodonium ylides.

Efficient one-pot synthesis of multi-substituted dihydrofurans by ruthenium(II)-catalyzed [3+2] cycloaddition of cyclic or acyclic diazodicarbonyl compounds with olefins

Ruthenium(II)-phosphine complexes-catalyzed [3+2] cycloadditions were conducted to synthesize a variety of dihydrofurans by reactions of cyclic or acyclic diazodicarbonyl compounds with olefins. This method represents a direct and efficient one-pot synthesis for multi-substituted dihydrofurans under mild reaction conditions with an excellent regioselectivity. Furthermore, to reduce reaction times and increase yields of dihydrofurans, microwave-as sisted tris(triphenylphosphine)ruthenium(II) chloride/ 1-butyl-3-methylimidazolium tetrafluoroborate {Ru (PPh3)3Cl2/ [Bmim]BF4}-catalyzed reactions were also developed. The synthesized dihydrofurans can be readily converted into biologically interesting tetrahydroindoles.

AgBF4/[Bmim]BF4-Catalyzed [3+2] cycloaddition of cyclic diazodicarbonyl compounds: Efficient synthesis of 2,3-dihydrofurans and conversion to 3-acylfurans

A novel and efficient method for the synthesis of 2,3-dihydrofurans bearing a variety of substituents on the dihydrofuran ring was achieved by the reaction of cyclic diazodicarbonyl compounds with styrene and vinyl acetate. The key strategy was AgBF4

Regioselective Synthesis of Dihydrofurans from 2,2-Dibromo 1,3-Diones and Olefins Using Copper

2,2-Dibromo 1,3-diones reacted with copper powder and olefin to give 2,3-dihydrofuran derivatives in a highly regioselective fashion.Acetylenes and 1,3-dienes also reacted with 2,2-dibromo 1,3-diones and copper to afford furan derivatives and 2-vinyl-2,3-

ELECTROCHEMICAL REDUCTION OF DIBROMODIKETONES FACILE CYCLOADDITION WITH OLEFINS

Electrochemical reduction of 2,2-dibromo-1,3-diketones in the presence of olefins afforded the cycloadducts, 2,3-dihydrofuran derivatives, regioselectively.

REGIOSELECTIVE SYNTHESIS OF DIHYDROFURANS FROM 2,2-DIBROMO-1,3-DIKETONE AND OLEFIN USING COPPER

2,2-Dibromo-1,3-diketones reacted with copper powder and olefin to give 4,5-dihydrofuran derivatives in a highly regioselective fashion.