929016-65-9Relevant academic research and scientific papers
Ratiometric electrochemical detection of β-galactosidase
Spring, Sam A.,Goggins, Sean,Frost, Christopher G.
, p. 7122 - 7126 (2017)
A novel ferrocene-based substrate for the ratiometric electrochemical detection of β-galactosidase was designed and synthesised. It was demonstrated to be an excellent electrochemical substrate for β-Gal detection with sensitivity as low as 0.1 U mL-1.
COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF
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Page/Page column 185-187, (2020/07/21)
Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a SO2 functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.
Studies on the synthesis and antiproliferative activities of 13-cis-retinoyl sugar derivatives
Xiang, Jian-Nan,Jiang, Li-Hui,Chen, Chao-Yue,Fu, Zhi-Ying,Duan, Jun-Fei,He, Xiao-Xiao,Wang, Ke-Min
, p. 595 - 614 (2007/10/03)
New retinoyl sugar derivatives of 13-cis-retinoic acid were synthesized in three ways in this paper in order to enhance pharmacal effects, especially antiproliferative activities of 13-cis-retinoic acid. Their structures were confirmed by IR, 1H-NMR, 13C-NMR, and MS spectra and their antiproliferative activities were determined in vitro using human cancer lines. Results showed that some compounds possessed potential antitumor activities. Copyright Taylor & Francis Group, LLC.
