929040-05-1

Basic information

• Product Name: Methyl 5-[(4-bromo-2-nitrophenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]-ethyl}oxy)thiophene-2-carboxylate
• Synonyms: Methyl 5-[(4-bromo-2-nitrophenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]-ethyl}oxy)thiophene-2-carboxylate
• CAS NO: 929040-05-1
• Molecular Weight: 545.334
• Mol File: 929040-05-1.mol

Chemical Properties

• CAS DataBase Reference: Methyl 5-[(4-bromo-2-nitrophenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]-ethyl}oxy)thiophene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-[(4-bromo-2-nitrophenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]-ethyl}oxy)thiophene-2-carboxylate(929040-05-1)
• EPA Substance Registry System: Methyl 5-[(4-bromo-2-nitrophenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]-ethyl}oxy)thiophene-2-carboxylate(929040-05-1)

Safety Data

• Hazardous Substances Data: 929040-05-1(Hazardous Substances Data)

Upstream product

• 929039-92-9 methyl 5-amino-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)-2-thiophenecarboxylate 
• 3460-18-2 1,4-dibromo-2-nitrobenzene 

Downstream Products

• 929040-07-3 Methyl 5-[(2-amino-4-bromophenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]-ethyl}oxy)thiophene-2-carboxylate 

Relevant articles and documents

5- AND 6- SUBSTITUTED BENZIMIDAZOLE THIOPHENE COMPOUNDS

The present invention provides 5- and 6-substituted benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.

Regioselective synthesis of benzimidazole thiophene inhibitors of polo-like kinase 1

A regioselective synthesis of novel 1-(2-thienyl)-benzimidazole inhibitors of polo-like kinase 1 is described. Amination of substituted 2-iodo or -bromo nitrobenzenes with a 2-aminothiophene derivative catalyzed by Pd2dba3 and XANTPH

BENZIMIDAZOLE THIOPHENE COMPOUNDS AS PLK MODULATORS

The present invention provides 5-heteroaryl substituted benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.

REGIOSELECTIVE PROCESS FOR PREPARING BENZIMIDAZOLE THIOPHENES

The present invention provides a process for preparing benzimidazole thiophene compounds of formula I. Intermediates used in the process are also claimed.