929039-92-9

Usage

Uses

Used in Pharmaceutical Industry:
2-Thiophenecarboxylic acid, 5-aMino-3-[(1R)-1-[2-(trifluoroMethyl)phenyl]ethoxy]-, Methyl ester is used as a pharmaceutical intermediate for the synthesis of various drugs and drug candidates. Its unique structure and functional groups make it a valuable building block in the development of new therapeutic agents.
Used in Agrochemical Industry:
2-Thiophenecarboxylic acid, 5-aMino-3-[(1R)-1-[2-(trifluoroMethyl)phenyl]ethoxy]-, Methyl ester is used as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its specific functional groups can be utilized to create compounds with targeted biological activity against pests and weeds.
Used in Materials Science:
2-Thiophenecarboxylic acid, 5-aMino-3-[(1R)-1-[2-(trifluoroMethyl)phenyl]ethoxy]-, Methyl ester is used in the development of new materials with specific properties, such as conductive polymers, sensors, and other electronic devices. Its aromatic thiophene ring and functional groups contribute to the desired characteristics of these materials.

Upstream product

• 89380-77-8 methyl 3-hydroxy-5-nitrothiothiophene-2-carboxylate 
• 79756-81-3 (S)-1-(2-trifluoromethylphenyl)ethanol 
• 929039-94-1 methyl 5-nitro-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)-2-thiophenecarboxylate 

Downstream Products

• 929040-05-1 Methyl 5-[(4-bromo-2-nitrophenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]-ethyl}oxy)thiophene-2-carboxylate 
• 929095-36-3 methyl 5-[(5-{[(2,2-dimethylpropanoyl)oxy]methyl}-2-nitrophenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)thiophene-2-carboxylate 
• 929095-53-4 methyl 5-[(5-{[(methyloxy)methyl]oxy}-2-nitrophenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)-2-thiophenecarboxylate 
• 929095-58-9 methyl 5-({5-[bis(methyloxy)methyl]-2-nitrophenyl}amino)-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)-2-thiophenecarboxylate 
• 1082337-64-1 C₂₉H₂₅F₃N₂O₇S 
• 929095-72-7 methyl 5-{[5-({[4-(methyloxy)phenyl]methyl}oxy)-2-nitrophenyl]amino}-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)-2-thiophenecarboxylate 
• 1082337-79-8 C₂₂H₁₆F₆N₂O₆S 
• 1082337-76-5 C₂₂H₁₆F₃N₃O₅S 
• 1082337-59-4 C₂₁H₁₇F₃N₂O₅S 
• 1082337-60-7 C₂₇H₂₀F₃N₃O₇S 
• 929095-37-4 methyl 5-[(2-amino-5-{[(2,2-dimethylpropanoyl)oxy]methyl}phenyl)amino]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)thiophene-2-carboxylate 
• 929095-38-5 methyl 5-(6-{[(2,2-dimethylpropanoyl)oxy]methyl}-1H-benzimidazol-1-yl)-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)thiophene-2-carboxylate 
• 929095-39-6 methyl 5-[6-(hydroxymethyl)-1H-benzimidazol-1-yl]-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)thiophene-2-carboxylate 
• 1094554-41-2 D-Methyl 5-({5-[(4-methyl-1-piperazinyl)methyl]-2-nitrophenyl}amino)-3-({(1R)-1-[2-(trifluoromethyl)phenyl]ethyl}oxy)-2-thiophenecarboxylate 

Relevant academic research and scientific papers

BENZIMIDAZOLE THIOPHENE DERIVATIVE COMPOUNDS INDUCING SELECTIVE DEGRADATION OF PLK1

The present invention provides novel compounds that induce selective polo-like kinase 1 (PLK1) degradation. Specifically, the present invention provides a bifunctional compound in which a PLK1 binding moiety and an E3 ubiquitin ligase-binding moiety are l

5- AND 6- SUBSTITUTED BENZIMIDAZOLE THIOPHENE COMPOUNDS

The present invention provides 5- and 6-substituted benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.

Benzimidazole Thiophene Compounds

The present invention provides benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.

Regioselective synthesis of benzimidazole thiophene inhibitors of polo-like kinase 1

A regioselective synthesis of novel 1-(2-thienyl)-benzimidazole inhibitors of polo-like kinase 1 is described. Amination of substituted 2-iodo or -bromo nitrobenzenes with a 2-aminothiophene derivative catalyzed by Pd2dba3 and XANTPH

BENZIMIDAZOLE THIOPHENE COMPOUNDS

The present invention provides benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.

BENZIMIDAZOLE THIOPHENE COMPOUNDS AS PLK MODULATORS

The present invention provides 5-heteroaryl substituted benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.

BENZIMIDAZOLE THIOPHENE COMPOUNDS

The present invention provides benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.

REGIOSELECTIVE PROCESS FOR PREPARING BENZIMIDAZOLE THIOPHENES

The present invention provides a process for preparing benzimidazole thiophene compounds of formula I. Intermediates used in the process are also claimed.