929049-06-9

Upstream product

• 135473-59-5 α-O,O'-diethyl amino(4-fluorophenyl)methylphosphonate 
• 98-09-9 benzenesulfonyl chloride 
• 98-10-2 benzenesulfonamide 
• 459-57-4 4-fluorobenzaldehyde 
• 762-04-9 phosphonic acid diethyl ester 

Relevant academic research and scientific papers

Sulfonamide derivative as well as preparation method and application thereof

The invention discloses a sulfonamide derivative in the field of antibacterial compounds. The sulfonamide derivative has a structural formula as shown in formula II: (as shown in the specification); and the preparation method comprises the following steps

N-sulfonyl-and N-phosphorylbenzimidoylphosphonates

A procedure for preparing N-sulfonyl-and N- phosphorylbenzimidoylphosphonates by oxidation of the corresponding α-(sulfonylamino)-and α-(phosphorylamino)benzylphosphonates was developed. The σ constants of imidoylphosphonate groups were evaluated by 19F NMR spectroscopy, and specific features of their electronic effects were considered. The reactions of the imidoylphosphonates obtained with O-, S-, P-, and N-nucleophiles were studied. The phosphonate-phosphoramidate rearrangement of α-aminobenzylidene-bisphosphonates was found. Nauka/Interperiodica 2006.