929080-55-7

Basic information

• Product Name: 2(1H)-Pyridinone, 4-(3,5-dimethylphenoxy)-5-ethyl-6-methyl-3-(methylthio)-
• CAS NO: 929080-55-7
• Molecular Formula: C17H21NO2S
• Molecular Weight: 303.425
• Mol File: 929080-55-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2(1H)-Pyridinone, 4-(3,5-dimethylphenoxy)-5-ethyl-6-methyl-3-(methylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyridinone, 4-(3,5-dimethylphenoxy)-5-ethyl-6-methyl-3-(methylthio)-(929080-55-7)
• EPA Substance Registry System: 2(1H)-Pyridinone, 4-(3,5-dimethylphenoxy)-5-ethyl-6-methyl-3-(methylthio)-(929080-55-7)

Safety Data

• Hazardous Substances Data: 929080-55-7(Hazardous Substances Data)

Upstream product

• 624-92-0 Dimethyldisulphide 
• 651778-63-1 4-(3,5-dimethyl-phenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one 
• 121771-61-7 dichloro-3,5-dimethyliodobenzene 
• 172469-75-9 5-ethyl-4-hydroxy-6-methylpyridin-2(1H)-one 

Relevant articles and documents

Structure-activity relationship in the 3-iodo-4-phenoxypyridinone (IOPY) series: The nature of the C-3 substituent on anti-HIV activity

As part of a systematic SAR study on the 3-iodo-4-phenoxypyridinone 3 (IOPY) type non-nucleoside reverse transcriptase inhibitors, the analogues 4a-4z bearing different C-3 substituents were synthesized and evaluated for their anti-HIV activity against wild-type HIV-1 and four of the principal HIV mutant strains (K103N, Y181C, Y188L, and I100L). The results show that the 3-vinyl analogue 4j is the only compound which displays anti-HIV activity comparable to IOPY 3, and in this respect represents a possible back-up to this lead molecule.