929083-97-6

Basic information

• Product Name: L-(-)-3-(4-nitrophenyl)lactic acid methyl ester
• Synonyms: L-(-)-3-(4-nitrophenyl)lactic acid methyl ester
• CAS NO: 929083-97-6
• Molecular Weight: 225.201
• Mol File: 929083-97-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-(-)-3-(4-nitrophenyl)lactic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-(-)-3-(4-nitrophenyl)lactic acid methyl ester(929083-97-6)
• EPA Substance Registry System: L-(-)-3-(4-nitrophenyl)lactic acid methyl ester(929083-97-6)

Safety Data

• Hazardous Substances Data: 929083-97-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 33173-27-2 (S)-3-(4-nitrophenyl)-2-hydroxypropionic acid 

Downstream Products

• 1170960-20-9 (S)-2-butoxy-3-(4-nitrophenyl)propanoic acid methyl ester 
• 1170960-17-4 (S)-2-ethoxy-3-(4-nitrophenyl)propanoic acid methyl ester 
• 1170960-18-5 (S)-3-(4-nitrophenyl)-2-propoxypropanoic acid methyl ester 
• 1021692-54-5 (S)-2-methoxy-3-(4-nitrophenyl)propanoic acid methyl ester 
• 769969-68-8 (S)-3-(4-nitro-phenyl)-2-trifluoromethanesulfonyloxypropionic acid methyl ester 

Relevant articles and documents

Synthesis and evaluation of some novel isochroman carboxylic acid derivatives as potential anti-diabetic agents

A series of novel isochroman mono-carboxylic acid derivatives were synthesized, characterized and evaluated for their ability to inhibit protein tyrosine phosphatase 1B (PTP1B) in vitro in order to use them as potential anti-diabetic agents. Analysis of structure-activity relationships led to the identification of potent compound 4n which inhibited PTP1B with IC50 value of 51.63 ± 0.91 nM. In general, high potency was associated with a dithiolane ring with a spacer of five carbons to the isochroman ring. Compound 4n has been selected for in vivo evaluation as drug candidate for anti-diabetic activity.