92912-02-2

Basic information

• Product Name: 2H-Pyran-2-one, tetrahydro-6-methylene-4-phenyl-
• CAS NO: 92912-02-2
• Molecular Formula: C12H12O2
• Molecular Weight: 188.226
• Mol File: 92912-02-2.mol

Chemical Properties

• CAS DataBase Reference: 2H-Pyran-2-one, tetrahydro-6-methylene-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-2-one, tetrahydro-6-methylene-4-phenyl-(92912-02-2)
• EPA Substance Registry System: 2H-Pyran-2-one, tetrahydro-6-methylene-4-phenyl-(92912-02-2)

Safety Data

• Hazardous Substances Data: 92912-02-2(Hazardous Substances Data)

Upstream product

• 1187330-17-1 5-bromo-3-phenylhex-5-enoic acid 
• 92898-16-3 3-phenyl-5-hexynoic acid 

Downstream Products

• 99512-42-2 methyl 5-oxo-3-phenylhexanoate 
• 6049-47-4 5-oxo-3-phenylhexanoic acid 

Relevant articles and documents

OBTENTION DE δ-METHYLENE δ-LACTONES ET DE δ-LACTONES γ-ETHYLENIQUES

Cyclisation in the presence of a catalytic amount of yellow mercury (II) oxide of δ-acetylenic acids and γ-allenic acids leads respectively to δ-methylene-δ-lactones and γ-ethylenic-δ-lactones.

Synthesis of enol lactones via Cu(I)-catalyzed intramolecular O-vinylation of carboxylic acids

With the catalysis of Cul/trans-W,W-dimethylcyclohexane-1,2-diamine, a number of carboxylic acids underwent efficient intramolecular O-vinylation with vinyl bromides leading to the synthesis of the corresponding five- and six-membered enol lactones. The same catalytic system also led to the efficient cycloisomerization of alkynoic acids.

Resolution and Determination of the Absolute Stereochemistry of α- and β-Aryl-Substituted γ-Methylenevalerolactones, Alternate Substrate Inhibitors for Serine Proteases

To study the enantioselectivity of alternate substrate inhibition of chymotrypsin by chiral α- and β-arylsubstituted enol lactones, we have prepared four of these lactones in homochiral form: 3-phenyl-6-methylenetetrahydro-2-pyranone (αPh6H, IIa), 3-(1-na

Enol Lactone Inhibitors of Serine Proteases. The Effect of Regiochemistry on the Inactivation Behavior of Phenyl-Substituted (Halomethylene)tetra- and -dihydrofuranones and (Halomethylene)tetrahydropyranones toward α-Chymotrypsin: Stable Acyl Enzyme Inter

We have found that α-aryl-substituted halo enol lactones (I and II) are effective mechanism-based inactivators for chymotrypsin.In this study, we have investigated, for comparative purposes, halo enol lactones with aryl functions situated β and γ to the l