929217-82-3

Upstream product

• 85317-52-8 methyl 2-amino-3-(4-nitrophenyl)propionate 
• 17193-40-7 (+)-Methyl 2-amino-3-(4-nitrophenyl)propionate hydrochloride 
• 1991-83-9 4-nitrophenylalanine 
• 929217-80-1 2-(2-tert-butoxycarbonylamino-acetylamino)-3-(4-nitro-phenyl)-propionic acid methyl ester 
• 929217-81-2 {[1-(2-amino-ethylcarbamoyl)-2-(4-nitro-phenyl)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester 

Downstream Products

• 929217-83-4 3-(4-nitrobenzyl)triethylenetetraamine 

Relevant academic research and scientific papers

Synthesis and evaluation of a novel samarium-153 bifunctional chelating agent for radioimmunotargeting applications

A new bifunctional chelating agent (BCA), 3-(4-isothiocyanatobenzyl) triethylenetetraaminehexaacetic acid (9), has been synthesized in fast and easy conditions. An improved synthesis of its position isomer 1-(4- isothiocyanatobenzyl)triethylenetetraaminehexaacetic acid (19) is also described. Stability in serum media of the two corresponding aminobenzyl derivatives-samarium-153 complexes, respectively, 3-(4-aminobenzyl) triethylenetetraaminehexaacetic acid-samarium-153 and 1-(4-aminobenzyl) triethylenetetraaminehexaacetic acid-samarium-153, have been evaluated. The 3-(4-aminobenzyl)triethylenetetraaminehexaacetic acid complex revealed excellent stability in serum media, and therefore 3-(4-isothiocyanatobenzyl) triethylenetetraaminehexaacetic acid (9) appears useful for future in vivo radioimmunotherapy investigations. Copyright