85317-52-8

Basic information

• Product Name: 4-NITRO-PHENYLALANINE METHYL ESTER
• Synonyms: 4-NITRO-PHENYLALANINE METHYL ESTER;Nitro phenylalanine methyl ester;methyl 2-amino-3-(4-nitrophenyl)propionate
• CAS NO: 85317-52-8
• Molecular Formula: C₁₀H₁₂N₂O₄
• Molecular Weight: 224.21
• Mol File: 85317-52-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 360 °C at 760 mmHg
• Flash Point: 171.5 °C
• Appearance: /
• Density: 1.283 g/cm³
• Vapor Pressure: 2.29E-05mmHg at 25°C
• Refractive Index: 1.564
• PKA: 6.45±0.33(Predicted)
• CAS DataBase Reference: 4-NITRO-PHENYLALANINE METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-NITRO-PHENYLALANINE METHYL ESTER(85317-52-8)
• EPA Substance Registry System: 4-NITRO-PHENYLALANINE METHYL ESTER(85317-52-8)

Safety Data

• Hazardous Substances Data: 85317-52-8(Hazardous Substances Data)

Usage

General Description

4-NITRO-PHENYLALANINE METHYL ESTER is a chemical compound that is a methyl ester derivative of 4-nitrophenylalanine. 4-NITRO-PHENYLALANINE METHYL ESTER is used in various biochemical research studies as a precursor for the synthesis of peptides and proteins. It is also utilized in the study of enzyme kinetics and for the development of new drugs and pharmaceuticals. Additionally, 4-NITRO-PHENYLALANINE METHYL ESTER is a valuable tool in understanding the structure-activity relationship of different compounds and their biological functions. However, it is important to handle this chemical with caution due to its potential for toxicity and harmful effects on the environment.

InChI:InChI=1/C10H12N2O4/c1-16-10(13)9(11)6-7-2-4-8(5-3-7)12(14)15/h2-5,9H,6,11H2,1H3

Upstream product

• 67-56-1 methanol 
• 1991-83-9 4-nitrophenylalanine 
• 17193-40-7 (+)-Methyl 2-amino-3-(4-nitrophenyl)propionate hydrochloride 

Downstream Products

• 120330-86-1 methyl N-formyl-(4-nitro)phenylalaninate 
• 623144-14-9 methyl 2-[(2,6-dichlorobenzoyl)amino]-3-(4-nitrophenyl)propanoate 
• 105359-56-6 2-amino-3-(4-nitrophenyl)propanamide 
• 1353022-72-6 N-(1-{4,7-bis[(4-methylphenyl)sulfonyl]-1,4,7-triazonan-1-yl}-3-(4-nitrophenyl)propan-2-yl)-4-methylbenzene-1-sulfonamide 
• 1353022-74-8 N-[1-amino-3-(4-nitrophenyl)propan-2-yl]-4-methylbenzene-1-sulfonamide 
• 1353022-73-7 2-[(4-methylphenyl)sulfonamido]-3-(4-nitrophenyl)propanamide 
• 1005484-25-2 1-(4-nitrobenzyl)-2-(1,4,7-triazacyclononan-1-yl)ethylamine 
• 605670-02-8 N¹-(3-amino-propyl)-3-(4-nitro-phenyl)-propane-1,2-diamine 
• 605670-01-7 DL-p-nitrophenylalanate N-(3-aminopropyl) amide 
• 1160845-66-8 methyl α-(4-nitrobenzyl)diazoacetate 
• 89288-22-2 2-amino-3-(4-nitrophenyl)propan-1-ol 
• 220847-34-7 4-nitro-N-[(2,6-dimethylphenyl)carbonyl]-L-phenylalanine methyl ester 
• 160132-37-6 4-[2-(n-butylsulfonylamino)-2-(methoxy-carbonyl)-ethyl]-aniline 
• 623146-90-7 methyl 2-[(2,6-dichlorobenzyl)amino]-3-(4-nitrophenyl)propanoate 

Relevant articles and documents

Ligand and metal complex

A ligand of Formula (I) is provided: wherein A4 represents a hydrogen atom, a nitro group, an amino group, a thiocyanato group, or —Z—Y, in which Z is a divalent linking group and Y is a group derived from a biocompatible molecule, with the proviso that when X is methylene, A4 cannot be a hydrogen atom or a nitro group. A metal complex having the ligand is also provided and is useful as a blood pool contrast agent or a targeting contrast agent.

Synthesis and evaluation of a novel samarium-153 bifunctional chelating agent for radioimmunotargeting applications

A new bifunctional chelating agent (BCA), 3-(4-isothiocyanatobenzyl) triethylenetetraaminehexaacetic acid (9), has been synthesized in fast and easy conditions. An improved synthesis of its position isomer 1-(4- isothiocyanatobenzyl)triethylenetetraaminehexaacetic acid (19) is also described. Stability in serum media of the two corresponding aminobenzyl derivatives-samarium-153 complexes, respectively, 3-(4-aminobenzyl) triethylenetetraaminehexaacetic acid-samarium-153 and 1-(4-aminobenzyl) triethylenetetraaminehexaacetic acid-samarium-153, have been evaluated. The 3-(4-aminobenzyl)triethylenetetraaminehexaacetic acid complex revealed excellent stability in serum media, and therefore 3-(4-isothiocyanatobenzyl) triethylenetetraaminehexaacetic acid (9) appears useful for future in vivo radioimmunotherapy investigations. Copyright

Biospecific binding reactants labelled with luminescent lanthanide chelates and their use

This invention relates to a detectable molecule comprising a biospecific binding reactant attached to a luminescent lanthanide chelate comprising a lanthanide ion and a chelating ligand of the formula STR1 wherein --A-- is a bivalent aromatic structure se