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929252-65-3

1-Piperidinecarboxylic acid, 4-[[[4-(4-amino-2-fluorophenoxy)-6-methoxy-7-quinolinyl]oxy]methyl]-, 1,1-dimethylethyl ester, commonly known as trelagliptin, is a complex organic compound that functions as a dipeptidyl peptidase-4 (DPP-4) inhibitor. It is utilized in the medical field for the treatment of type 2 diabetes, where it plays a crucial role in regulating blood sugar levels.
Used in Pharmaceutical Industry:
Trelagliptin is used as an antidiabetic medication for the treatment of type 2 diabetes. It operates by inhibiting the DPP-4 enzyme, which is responsible for breaking down incretin hormones. This inhibition leads to an increase in the levels of incretin hormones, stimulating the release of insulin and reducing glucose production in the liver, ultimately resulting in improved blood sugar control for patients with type 2 diabetes.

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  • 1-Piperidinecarboxylic acid, 4-[[[4-(4-amino-2-fluorophenoxy)-6-methoxy-7-quinolinyl]oxy]methyl]-, 1,1-dimethylethyl ester

    Cas No: 929252-65-3

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  • tert-Butyl 4-(((4-(4-amino-2-fluorophenoxy)-6-methoxyquinolin-7-yl)oxy)methyl)piperidine-1-carboxylate Cas no.929252-65-3 98%

    Cas No: 929252-65-3

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  • 929252-65-3 Structure

  • Basic information

    1. Product Name: 1-Piperidinecarboxylic acid, 4-[[[4-(4-amino-2-fluorophenoxy)-6-methoxy-7-quinolinyl]oxy]methyl]-, 1,1-dimethylethyl ester
    2. Synonyms:
    3. CAS NO:929252-65-3
    4. Molecular Formula: C27H32FN3O5
    5. Molecular Weight: 497.567
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 929252-65-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-Piperidinecarboxylic acid, 4-[[[4-(4-amino-2-fluorophenoxy)-6-methoxy-7-quinolinyl]oxy]methyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 4-[[[4-(4-amino-2-fluorophenoxy)-6-methoxy-7-quinolinyl]oxy]methyl]-, 1,1-dimethylethyl ester(929252-65-3)
    11. EPA Substance Registry System: 1-Piperidinecarboxylic acid, 4-[[[4-(4-amino-2-fluorophenoxy)-6-methoxy-7-quinolinyl]oxy]methyl]-, 1,1-dimethylethyl ester(929252-65-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 929252-65-3(Hazardous Substances Data)

929252-65-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 929252-65-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,9,2,5 and 2 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 929252-65:
(8*9)+(7*2)+(6*9)+(5*2)+(4*5)+(3*2)+(2*6)+(1*5)=193
193 % 10 = 3
So 929252-65-3 is a valid CAS Registry Number.

929252-65-3Relevant articles and documents

Preparation method of aryloxy quinoline compound

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Paragraph 0059; 0072-0076; 0092-0094; 0101-0103; 0110-0112, (2021/04/29)

The invention provides a preparation method of an aryloxy quinoline compound, and particularly provides a method for preparing an aryloxy quinoline compound with a structure shown in a formula (I) by taking 4-chloro-6-methoxy-7-quinolinol as a starting ra

PHARMACEUTICALLY ACTIVE COMPOUNDS AS AXL INHIBITORS

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Page/Page column 105, (2012/03/26)

The present invention relates to 1-nitrogen-heterocyclic-2-carboxamides of general formula (I): and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the treatment and/or prevention of Axl receptor tyrosine kinase subfamily induced disorders, including cancer and primary tumor metastases, and pharmaceutical compositions containing at least one of said 1-nitrogen-heterocyclic-2-carboxamide derivatives and/or pharmaceutically acceptable salts thereof.

Pharmaceutically active compounds as Axl inhibitors

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Paragraph 0140, (2013/03/26)

The present invention relates to 1-nitrogen-heterocyclic-2-carboxamides of general formula (I): and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the treatment and/or prevention of Axl receptor tyrosine kinase subfamily induced disorders, including cancer and primary tumor metastases, and pharmaceutical compositions containing at least one of said 1-nitrogen-heterocyclic-2-carboxamide derivatives and/or pharmaceutically acceptable salts thereof.

Met kinase inhibitors

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Page/Page column 17-18, (2010/11/26)

The present invention is directed to compounds that are useful for treating cancer having one of the following Formulas:

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