849217-45-4

Usage

Uses

Used in Pharmaceutical Industry:
1-Piperidinecarboxylic acid, 4-[[[4-(2-fluoro-4-nitrophenoxy)-6-methoxy-7-quinolinyl]oxy]methyl]-, 1,1-dimethylethyl ester is used as a potential drug candidate for the treatment of certain diseases or conditions due to its unique structure and bioactivity. The presence of quinoline and piperidine groups in its composition suggests that it may have therapeutic properties that can be further explored and developed.
Further research and testing are required to fully understand the potential uses and effects of 1-Piperidinecarboxylic acid, 4-[[[4-(2-fluoro-4-nitrophenoxy)-6-methoxy-7-quinolinyl]oxy]methyl]-, 1,1-dimethylethyl ester in the pharmaceutical industry. Its complex structure and the presence of various functional groups indicate that it may have specific interactions with biological targets, making it a promising candidate for drug development.

Upstream product

• 479690-08-9 1-(2-fluoro-4-nitrophenyl)-6-hydroxy-7-methoxy-quinoline 
• 161975-39-9 tert-butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate 
• 929252-63-1 hydrobromide salt of 4-(2-fluoro-4-nitrophenoxy)-6-methoxy-7-hydroxyquinoline 
• 479690-03-4 7-benzyloxy-4-(2-fluoro-4-nitro-phenoxy)-6-methyloxyquinoline 
• 75665-73-5 1-(2-amino-4-(benzyloxy)-5-methoxyphenyl)ethanone 
• 205448-29-9 7-benzyloxy-4-hydroxy-6-methoxyquinoline 
• 1835-11-6 4-benzyloxy-3-methoxyacetophenone 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 75665-88-2 1-(4-(benzyloxy)-5-methoxy-2-nitrophenyl)ethanone 
• 166815-96-9 N-tert-butoxycarbonyl-4-(4-toluenesulphonyloxymethyl)piperidine 
• 403-19-0 2-fluoro-4-nitrophenol 

Downstream Products

• 929252-65-3 tert-butyl 4-(((4-(4-amino-2-fluorophenoxy)-6-methoxyquinolin-7-yl)oxy)methyl)piperidine-1-carboxylate 
• 849217-47-6 3-fluoro-4-((6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinolin-4-yl)oxy)aniline 

Relevant academic research and scientific papers

Preparation method of aryloxy quinoline compound

The invention provides a preparation method of an aryloxy quinoline compound, and particularly provides a method for preparing an aryloxy quinoline compound with a structure shown in a formula (I) by taking 4-chloro-6-methoxy-7-quinolinol as a starting ra

Met kinase inhibitors

The present invention is directed to compounds that are useful for treating cancer having one of the following Formulas:

C-MET MODULATORS AND METHODS OF USE

The present invention provides compounds, which have activity for modulating protein kinase enzymatic activity and are potentially useful for modulating cellular activities such as, e.g., proliferation, differentiation, programmed cell death, migration and chemoinvasion. The present invention also provides compositions containing such compounds, and methods for producing and using such compounds and compositions.

C-MET MODULATORS AND METHODS OF USE

The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate and/or modulate kinase receptor, particularly c-Met, KDR, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.