92932-15-5

Basic information

• Product Name: 2-[(1,3-Dihydro-1,3-dioxo-2H-isoindole-2-yl)methyl]propanenitrile
• Synonyms: 2-[(1,3-Dihydro-1,3-dioxo-2H-isoindole-2-yl)methyl]propanenitrile;N-(2-Cyanopropyl)phthalimide;3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-2-methylpropanenitrile
• CAS NO: 92932-15-5
• Molecular Formula: C12H10N2O2
• Molecular Weight: 214.22
• Mol File: 92932-15-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[(1,3-Dihydro-1,3-dioxo-2H-isoindole-2-yl)methyl]propanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(1,3-Dihydro-1,3-dioxo-2H-isoindole-2-yl)methyl]propanenitrile(92932-15-5)
• EPA Substance Registry System: 2-[(1,3-Dihydro-1,3-dioxo-2H-isoindole-2-yl)methyl]propanenitrile(92932-15-5)

Safety Data

• Hazardous Substances Data: 92932-15-5(Hazardous Substances Data)

Upstream product

• 7223-50-9 N-propargylphthalimide 
• 74-90-8 hydrogen cyanide 
• 1074-82-4 potassium phtalimide 
• 117903-81-8 2-(2'-cyanoprop-2'-enyl)-1H-isoindole-1,3(2H)-dione 
• 136918-14-4 phthalimide 
• 126-98-7 methacrylonitrile 

Downstream Products

• 101642-77-7 (2R)-N-benzyloxycarbonyl-2-aminopropanecarboxylic acid 
• 28267-25-6 (RS)-2-(aminomethyl)propanoic acid hydrochloride 

Relevant articles and documents

Preparation method of alkyl nitrile compound

The invention discloses a preparation method of an alkyl nitrile compound. Specifically, the preparation method comprises the following step: in an organic solvent, in the presence of a protective gasand under the action of a catalyst, carrying out a reduction reaction as shown in the specification on olefin as shown in a formula I, a cyanation reagent and water, wherein the alkyl nitrile compound 1 is a compound II and/or a compound III. The preparation method provided by the invention is mild in condition, can realize hydrocyanation of olefin more safely and efficiently, and has good substrate universality and functional group compatibility.

The Stereochemistry of Organometallic Compounds. XXXII. Hydrocyanation of Derivatives of Amino Alkynes

The hydrocyanation of a range of amino alkyne derivatives has been studied by using nickel-based catalyst systems.The phthalimido derivatives have been shown to give good yields of unsaturated cyano amine derivatives, and some of these have been converted into both saturated and unsaturated amino acids.

Histamine analogues, XXVI: Racemic histamine H1-agonists

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