92934-94-6Relevant articles and documents
1,4- and 1,5-Stereoselection by Sequential Aldol Addition to α,β-Unsaturated Aldehydes Followed by Claisen Rearrangement. Application to Total Synthesis of the Vitamin E Side Chain and the Archaebacterial C40 Diol
Heathcock, Clayton H.,Finkelstein, Bruce L.,Jarvi, Esa T.,Radel, Peggy A.,Hadley, Cheri H.
, p. 1922 - 1942 (2007/10/02)
A synthetic strategy has been developed wherein the high 1,2-stereoselection obtainable from aldol reaction of an α,β-unsaturated aldehyde is parlayed by a subsequent Claisen rearrangement into 1,4- or 1,5-stereoselection.For example, diol monoethers 26 a
1,5-Acyclic stereoselection. The stereocontrolled synthesis of optically active vitamin E fourteen-carbon side chain alcohol
Berube,Deslongchamps
, p. 1558 - 1560 (2007/10/02)
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