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Upstream product

• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 1029793-19-8 C₁₅H₁₅N₃OS₂ 
• 70-11-1 α-bromoacetophenone 
• 6010-25-9 1-(4-methoxyphenyl)-3-(2-thienyl)propen-1-one 
• 98-03-3 thiophene-2-carbaldehyde 

Relevant academic research and scientific papers

Synthesis, biological evaluation and 3D-QSAR study of novel 4,5-dihydro-1H-pyrazole thiazole derivatives as BRAFV600E inhibitors

Many reports implied that the BRAF serine/threonine kinase was mutated in various types of human tumors, which were related with cell growth, survival and differentiation. To provide new therapeutic opportunities, a series of novel 4,5-dihydro-1H-pyrazole

Discovery and modification of sulfur-containing heterocyclic pyrazoline derivatives as potential novel class of β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitors

A series of sulfur-containing heterocyclic pyrazoline derivatives (C1-C18; D1-D9) have been synthesized and purified (all are new except one) to screen for FabH inhibitory activity. Compound C14 showed the most potent biological activity against Escherich