929602-14-2Relevant academic research and scientific papers
Intermolecular Dehydrative [4 + 2] Aza-Annulation of N-Arylamides with Alkenes: A Direct and Divergent Entrance to Aza-Heterocycles
Huang, Ying-Hong,Wang, Shu-Ren,Wu, Dong-Ping,Huang, Pei-Qiang
, p. 1681 - 1685 (2019/03/11)
We disclose that following activation with trifluoromethanesulfonyl anhydride, secondary N-arylamides undergo smooth intermolecular dehydrative [4 + 2] aza-annulation with alkenes under mild conditions to give 3,4-dihydroquinolines, amenable to further functionalization. Meanwhile, conditions have been established to allow divergent one pot synthesis of tetrahydroquinolines and quinolines as well as tricyclic analogues from N-arylamides.
Rh-catalyzed sequential hydroarylation/hydrovinylation-heterocyclization of β-(2-aminophenyl)-α,β-ynones with organoboron derivatives: A new approach to functionalized quinolines
Abbiati, Giorgio,Arcadi, Antonio,Marinelli, Fabio,Rossi, Elisabetta,Verdecchia, Mirella
, p. 3218 - 3224 (2008/09/17)
4-Aryl and 4-vinyl quinolines were prepared via a sequential procedure involving regioselective Rh(acac)(C2H2)/dppf-catalyzed hydroarylation/hydrovinylation of β-(2-aminophenyl)-α,β-ynones with arylboronic acids or potassium aryl and
