929617-29-8 Usage
Uses
Used in Pharmaceutical Industry:
6-BROMO-4-ETHYLPYRIDIN-3-AMINE is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Agrochemical Industry:
In the agrochemical sector, 6-BROMO-4-ETHYLPYRIDIN-3-AMINE is utilized as a building block for the creation of novel agrochemicals. Its chemical properties make it suitable for the design of effective pesticides, herbicides, and other crop protection agents.
Used in Dye Production:
6-BROMO-4-ETHYLPYRIDIN-3-AMINE is employed as a precursor in the production of dyes. Its chemical structure contributes to the development of dyes with specific color properties and stability, making it valuable in the textile, printing, and other industries that rely on colorants.
Used in Fine Chemicals Industry:
6-BROMO-4-ETHYLPYRIDIN-3-AMINE is also used in the production of fine chemicals, which are high-purity chemicals used in various applications such as research, diagnostics, and specialty manufacturing. The versatility of 6-BROMO-4-ETHYLPYRIDIN-3-AMINE makes it a valuable component in the synthesis of these high-quality chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 929617-29-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,9,6,1 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 929617-29:
(8*9)+(7*2)+(6*9)+(5*6)+(4*1)+(3*7)+(2*2)+(1*9)=208
208 % 10 = 8
So 929617-29-8 is a valid CAS Registry Number.
929617-29-8Relevant academic research and scientific papers
Design and synthesis of pyridine-pyrazolopyridine-based inhibitors of protein kinase B/Akt
Zhu, Gui-Dong,Gong, Jianchun,Gandhi, Viraj B.,Woods, Keith,Luo, Yan,Liu, Xuesong,Guan, Ran,Klinghofer, Vered,Johnson, Eric F.,Stoll, Vincent S.,Mamo, Mulugeta,Li, Qun,Rosenberg, Saul H.,Giranda, Vincent L.
, p. 2441 - 2452 (2007/10/03)
Thr-211 is one of three different amino acid residues in the kinase domain of protein kinase B/Akt as compared to protein kinase A (PKA), a closely related analog in the same AGC family. In an attempt to improve the potency and selectivity of our indazole-pyridine series of Akt inhibitors over PKA, efforts have focused on the incorporation of a chemical functionality to interact with the hydroxy group of Thr-211. Several substituents including an oxygen anion, amino, and nitro groups have been introduced at the C-6 position of the indazole scaffold, leading to a significant drop in Akt potency. Incorporation of a nitrogen atom into the phenyl ring at the same position (i.e., 9f) maintained the Akt activity and, in some cases, improved the selectivity over PKA. The structure-activity relationships of the new pyridine-pyrazolopyridine series of Akt inhibitors and their structural features when bound to PKA are also discussed.
