92962-44-2Relevant academic research and scientific papers
Copper Photoredox Catalyzed A3’ Coupling of Arylamines, Terminal Alkynes, and Alcohols through a Hydrogen Atom Transfer Process
Sagadevan, Arunachalam,Pampana, V. Kishore Kumar,Hwang, Kuo Chu
supporting information, p. 3838 - 3842 (2019/02/26)
The first successful example of the three-component coupling of N-alkylanilines, terminal alkynes, and alcohols was achieved at room temperature by a visible-light-mediated copper-catalyzed photoredox hydrogen-atom transfer process. This method allows pre
Cu/Fe-cocatalyzed meyer-schuster-like rearrangement of propargylic amines: Direct access to e -β-aminoacryaldehydes
Chen, Ming,Peng, Jiangling,Mao, Tingting,Huang, Jinbo
supporting information, p. 6286 - 6289 (2015/02/05)
A simple and efficient method for the synthesis of β-aminoacryaldehydes via Cu(OAc)2·H2O and FeCl3 cocatalyzed Meyer-Schuster-Like rearrangement of propargylic amines was developed. The reactions proceed selectively as the E-isomers in generally good yields under aerobic conditions, and are compatible with a broad range of functional groups. This method combines C-N bond cleavage as well as the N-aryl group migration and provides a practical and mild synthetic approach to α,β-unsaturated carbonyl compounds, which are useful precursors in a variety of functional group transformations.
