92964-08-4

Upstream product

• 55-22-1 pyridine-4-carboxylic acid 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 

Downstream Products

• 6344-93-0 5,7-dimethoxy-2-(pyridin-4-yl)-4H-chromen-4-one 
• 6344-88-3 1-(2-hydroxy-4,6-dimethoxy-phenyl)-3-pyridin-4-yl-propane-1,3-dione 

Relevant academic research and scientific papers

Design, synthesis, biological evaluation, and molecular docking of novel benzopyran and phenylpyrazole derivatives as Akt inhibitors

By inspiration of good Akt1 inhibitory and cytotoxic activity of our previously screened hits 1 and 2, a series of novel benzopyrans 3a-c, 4 and phenylpyrazoles 5a-c, 6a-b, and 7 were designed, synthesized, and biologically evaluated for their in vitro Ak

PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES

The present invention relates to polyphenol-like compounds that are useful for inhibiting VCAM-1 expression, MCP-1 expression and/or SMC proliferation in a mammal. The disclosed compounds are useful for regulating markers of inflammatory conditions, including vascular inflammation, and for treatment and prevention of inflammatory and cardiovascular diseases and related disease states.