929692-42-2Relevant academic research and scientific papers
Synthesis of lithium 1-alkynesulfenates by the mild oxidation of thiolates with a pinacolone-derived N-sulfonyloxaziridine
Sandrinelli, Franck,Boudou, Cédric,Caupène, Caroline,Averbuch-Pouchot, Marie-Thérèse,Perrio, Stéphane,Metzner, Patrick
, p. 3289 - 3293 (2006)
Lithium 1-alkynethiolates, generated by a base-induced ring cleavage of 4-substituted 1,2,3-thiadiazoles, were efficiently converted into the corresponding sulfenate salts by mild oxidation using an N-sulfonyloxaziridine derived from pinacolone. In situ S
An enantioselective approach to the preparation of chiral sulfones by ir-catalyzed asymmetric hydrogenation
Peters, Byron K.,Zhou, Taigang,Rujirawanich, Janjira,Cadu, Alban,Singh, Thishana,Rabten, Wangchuk,Kerdphon, Sutthichat,Andersson, Pher G.
, p. 16557 - 16562 (2015/01/09)
Several chiral sulfonyl compounds were prepared using the iridium catalyzed asymmetric hydrogenation reaction. Vinylic, allylic and homoallylic sulfone substitutions were investigated, and high enantioselectivity is maintained regardless of the location of the olefin with respect to the sulfone. Impressive stereoselectivity was obtained for dialkyl substitutions, which typically are challenging substrates in the hydrogenation. As expected, the more bulky Z-substrates were hydrogenated slower than the corresponding E isomers, and in slightly lower enantioselectivity.
