92982-05-3Relevant academic research and scientific papers
A solvent-free method for the preparation of phosphinates from P(O)-OH compounds with alkyl chlorides
Yuan, Huihui,Wang, Mingyue,Fan, Lei,Yang, Jia,Wang, Shuai,Zhong, Hong
supporting information, (2021/11/17)
Herein, a new solvent-free synthetic method using P(O)-OH compound and alkyl chloride for phosphinate compounds is disclosed. This transformation proceeds smoothly under the promotion of a lone base and presents the advantages of an easily available raw material source, a simple post treatment process, good functional group tolerance and high reaction efficiency. Good yield was obtained when the reaction was magnified to gram scale, and the molar ratio of P(O)-OH compounds and alkyl chlorides can be decreased to 1:2. This protocol provides a practical method for the preparation of phosphorus derivatives. Furthermore, the reaction mechanism was explored by means of 31P NMR.
Synthesis of phosphorus derivatives from 1,3-dioxolan-2-one
Ilia, Gheorghe,Bora, Alina,Iliescu, Smaranda,Popa, Adriana,Dehelean, Gheorghe
, p. 2491 - 2496 (2007/10/03)
A new route for the synthesis of some mixed organic phosphorus compounds from 1,3-dioxolan-2-one is reported. By heating a mixture of phosphorus-chlorine derivatives and 1,3-dioxolan-2-one in the presence of a catalyst, mixed phosphorus derivatives having 2-chloroethyl ester groups could be obtained. A wide range of phosphorus derivatives can be obtained using this method.
