929918-01-4

Upstream product

• 128510-88-3 tert-butyl (R)-2-(4-methylbenzenesulfonyloxymethyl)pyrrolidine-1-carboxylate 
• 103-16-2 4-Benzyloxyphenol 

Downstream Products

• 1006382-20-2 (R)-2-(4-prop-2-ynyloxy-phenoxymethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1006382-09-7 (R)-2-(4-prop-2-ynyloxy-phenoxymethyl)-pyrrolidine hydrochloride 
• 1006382-10-0 (R)-2-[4-(3-phenyl-prop-2-ynyloxy)-phenoxymethyl]-pyrrolidine hydrochloride 
• 929916-25-6 (R)-2-(4-benzyloxy-phenoxymethyl)-pyrrolidine hydrochloride 
• 929918-02-5 (R)-2-(4-hydroxy-phenoxymethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

PHENOXYMETHYLALKYNE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION

A chemical genus of biphenyl heterocycle derivative inhibitors of LTA4H (leukotriene A4 hydrolase) of the formula: is disclosed, hi these compounds Q and Z are (CH2)1.10; in which one or two (CH2) may optionally be replaced by -O-, -NR1-, -SO-, -S(O)2-, -

BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION

The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ: An example is