930-97-2Relevant academic research and scientific papers
One-pot synthesis of hypervalent diaryl(iodo)bismuthanes from o-carbonyl iodoarenes by zincation
Murafuji, Toshihiro,Hafizur Rahman,Magarifuchi, Daiki,Narita, Masahiro,Miyakawa, Isamu,Ishiguro, Katsuya,Kamijo, Shin
, (2019/04/25)
Diaryl(iodo)bismuthanes possessing a hypervalent C=O???Bi-I bond were conveniently synthesized in a one-pot reaction by using arylzinc reagents generated from o-carbonyl iodobenzenes and zinc powder under ultrasonication. This method is superior to the conventional organolithium and Grignard methods because it has a wide functional group tolerance, requires no protecting group manipulations, and proceeds under mild reaction conditions that do not need low temperature control. Furthermore, no intermediate triarylbismuthane precursor for the hypervalent iodobismuthane is necessary.
Selective metallation of 3-halothiophenes: Practical methods for the synthesis of 2-bromo-3-formylthiophene
Sonoda, Motohiro,Kinoshita, Shoko,Luu, Thanh,Fukuda, Hiroshi,Miki, Koji,Umeda, Rui,Tobe, Yoshito
experimental part, p. 3315 - 3323 (2011/03/20)
Selective lithiation of 3-bromothiophene was accomplished under controlled conditions without formation of undesired thienyllithium compounds. A thienyl Grignard reagent derived from 2-bromo-3-iodothiophene was transformed into 2-bromo-3-formylthiophene in high selectivity by formylation with dimethylformamide (DMF) at optimal reaction temperature. Copyright Taylor & Francis Group, LLC.
