26170-85-4

Basic information

• Product Name: 3-Phenyl-2-thiophenecarboxaldehyde
• Synonyms: 3-Phenyl-2-thiophenecarboxaldehyde;2-ForMyl-3-phenylthiophene
• CAS NO: 26170-85-4
• Molecular Formula: C₁₁H₈OS
• Molecular Weight: 188.24562
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 26170-85-4.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 313.4±30.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: 3-Phenyl-2-thiophenecarboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenyl-2-thiophenecarboxaldehyde(26170-85-4)
• EPA Substance Registry System: 3-Phenyl-2-thiophenecarboxaldehyde(26170-85-4)

Safety Data

• Hazardous Substances Data: 26170-85-4(Hazardous Substances Data)

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 591-50-4 iodobenzene 
• 4347-31-3 2-formylthiophene-3-boronic acid 
• 62-53-3 aniline 
• 930-96-1 3-bromo-2-thiophenecarboxaldehyde 
• 98-80-6 phenylboronic acid 
• 108-86-1 bromobenzene 
• 930-97-2 3-iodothiophene-2-carboxaldehyde 
• 71-43-2 benzene 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 
• 5918-68-3 (E)-N-phenyl-1-(thiophen-2-yl)methanimine 

Downstream Products

• 90690-41-8 2-formyl-3-phenylthiophene tosylhydrazone 
• 10341-88-5 3-phenyl-thiophen-2-carboxylic acid 
• 1068569-88-9 C₁₆H₁₃N₃S 
• 873581-61-4 (3-phenyl-thiophen-2-yl)-carbamic acid tert-butyl ester 
• 1579940-00-3 2-(3-phenyl-thiophen-2-ylcarbamoyl)-cyclopent-1-enecarboxylic acid 
• 128539-23-1 1-chloro-2,2-dimethyl-1-(3-phenylthiophen-2-yl)cyclopropane 
• 128539-15-1 1-chloro-3-methyl-2-(3-phenylthiophen-2-yl)but-2-ene 
• 157664-22-7 N-(3-phenyl-2-thienylmethyl)benzimidoyl chloride 
• 157664-13-6 2-benzamidomethyl-3-phenylthiophene 
• 157664-15-8 2-(aminomethyl)-3-phenylthiophene 
• 157664-14-7 3-phenylthiophene-2-carbaldehyde oxime 
• 128539-18-4 2-dichloromethyl-3-phenylthiophene 

Relevant articles and documents

FIBROBLAST GROWTH FACTOR 23 ANTAGONISTS AND RELATED COMPOSITIONS AND METHODS

This disclosure relates to small molecule inhibitors of Fibroblast growth factor 23 (FGF-23) and related compositions and methods of treatment.

GOLD-CATALYZED C-C CROSS-COUPLING OF BORON- AND SILICON-CONTAINING ARYL COMPOUNDS AND ARYLDIAZONIUM COMPOUNDS BY VISIBLE-LIGHT

The present invention relates to a method for producing (functionalized) biaryls by employing a visible-light-driven, gold-catalyzed C-C cross-coupling reaction system involving boron- and silicon-containing aryl compounds and aryldiazonium compounds. Moreover, the present invention relates to the use of such boron- and silicon-containing aryl compounds and aryldiazonium compounds, as well as related gold catalysts, in the manufacture of (functionalized) biaryls.

Photosensitizer-Free, Gold-Catalyzed C–C Cross-Coupling of Boronic Acids and Diazonium Salts Enabled by Visible Light

The first photosensitizer-free visible light-driven, gold-catalyzed C–C cross-couplings of arylboronic acids and aryldiazonium salts are reported. The reactions can be conducted under very mild conditions, using a catalytic amount of tris(4-trifluoromethyl)phosphinegold(I) chloride [(4-CF3-C6H4)3PAuCl] with methanol as the solvent allowing an alternative access to a variety of substituted biaryls in moderate to excellent yields with broad functional group tolerance. (Figure presented.).