93007-63-7Relevant academic research and scientific papers
TRNA SYNTHETASE INHIBITORS
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Paragraph 00123-00124, (2019/07/30)
Disclosed herein are secondary amine compounds that inhibit tRNA synthetase. The compounds of the invention are useful in inhibiting tRNA synthetase in Gram-negative bacteria and are useful in killing Gram-negative bacteria. The secondary amine compounds of the invention are also useful in the treatment of tuberculosis.
Benzocycloalkane derivatives and production thereof
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, (2008/06/13)
Benzocycloalkane derivative of the formula wherein R is a hydrogen atom or a hydrocarbon residue, which may optionally have one or more substituents, Ar is an aromatic group, X is an oxygen or sulfur atom, l is 0 or 1, m is 3 to 6 and n is 0 to 2, wherein the ring A and the group Ar each may optionally have one or more substituents, with the proviso that compounds are excluded, wherein Ar is whereby Rxand Ryare independently selected from alkyl or alkoxy of from one to seven carbon atoms, or its pharmaceutically acceptable salt, which is useful as inhibitors for acyl-CoA : cholesterolacyltransferase.
