93010-41-4 Usage
Uses
Used in Pharmaceutical Industry:
N-Benzyl-2-bromo-propionanilide is used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
N-Benzyl-2-bromo-propionanilide is used as a versatile building block in organic synthesis, enabling the creation of a wide range of complex organic molecules and compounds.
Used in Ni-pybox Catalyzed Asymmetric Negishi Couplings:
N-Benzyl-2-bromo-propionanilide is used as a reactant in Ni-pybox catalyzed asymmetric Negishi couplings, a type of cross-coupling reaction that allows for the formation of carbon-carbon bonds with high selectivity and enantioselectivity. This application is particularly useful in the synthesis of chiral molecules and compounds with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 93010-41-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,0,1 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 93010-41:
(7*9)+(6*3)+(5*0)+(4*1)+(3*0)+(2*4)+(1*1)=94
94 % 10 = 4
So 93010-41-4 is a valid CAS Registry Number.
93010-41-4Relevant academic research and scientific papers
Copper-Catalyzed Enantioselective Sonogashira Type Coupling of Alkynes with α-Bromoamides
Chen, Bin,Mo, Xueling,Zhang, Guozhu
supporting information, p. 13998 - 14002 (2020/06/10)
An asymmetric copper-catalyzed Sonogashira type coupling between alkynes and α-bromoamides has been developed. This method represents a facile approach to synthetically useful β, γ-alkynyl amides from two readily available starting materials in a highly enantioselective manner. A Bisoxazoline diphenylanaline (BOPA) serves as the effective chiral ligand. Preliminary mechanistic studies support the formation of alkyl radical species.
Asymmetric nickel-catalyzed Negishi cross-couplings of secondary α-bromo amides with organozinc reagents
Fischer, Christian,Fu, Gregory C.
, p. 4594 - 4595 (2007/10/03)
A Ni/Pybox catalyst achieves the asymmetric cross-coupling of secondary α-bromo amides with organozinc reagents. The process tolerates a variety of functional groups and affords the desired product in good yield and in high enantiomeric excess. Copyright
