93021-93-3

Usage

Chemical family

Benzene

Substituent groups

Methoxy group, phenylpropynyl ether group

Usage

Organic synthesis, potential applications in pharmaceuticals, fragrances, and other industries

Physical state

Colorless to pale yellow liquid

Properties (depending on conditions and environment)

Boiling point, solubility

Versatility and importance

Versatile and important chemical with various potential uses

Upstream product

• 150-76-5 4-methoxy-phenol 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 
• 21541-60-6 3-phenylprop-2-ynyl 4-methylbenzenesulfonate 
• 591-50-4 iodobenzene 
• 17061-86-8 1-methoxy-4-(2-propynyloxy)benzene 
• 3355-31-5 1-chloro-3-phenyl-2-propyne 

Downstream Products

• 876309-34-1 (Z)-3-(4-methoxyphenoxy)-1-phenylpropene 
• 21763-04-2 3,4-dihydro-4-phenyl-2H-chromene 
• 93021-99-9 6-methoxy-4-phenyl-2H-chromene 
• 1416006-27-3 6-methoxy-4-phenyl-2H-(3-²H)chromene 
• 104330-36-1 p-methoxybenzyl 3-phenylpropyl ether 
• 404580-71-8 (E)-1-methoxy-4-{[(3-phenylallyl)oxy]methyl}benzene 

Relevant academic research and scientific papers

Preparation method and application of propyne aryl ether compound

The invention particularly relates to a method for preparing propyne aryl ether compounds from aryl phenol, halogenated propyne and derivatives of the halogenated propyne, and belongs to the technical field of preparation of the propyne aryl ether compoun

Synthesis of 3-Organoselenyl-2H-Coumarins from Propargylic Aryl Ethers via Oxidative Radical Cyclization

A metal-free oxidative radical cyclization/selenylation of propargylic aryl ethers with diaryl diselenides was developed. This protocol provided an alternative method to synthesize 3-organoselenyl-2H-coumarins via the formation of C?Se bond, C?C bond, and C=O bond in one step. Moreover, a broad range of functional groups (such as halogen, aldehyde, ketone, cyano, and nitro group) were tolerated. (Figure presented.).

Synthesis of Tetrasubstituted α,β-Unsaturated Aldehydes via Radical 1,4-Aryl Migration/Trifluoromethylthiolation Cascade Reaction of Aryl Propynyl Ethers

A one-pot synthesis of tetrasubstituted acrylaldehydes via difunctionalization of aryl propynyl ethers has been achieved, which involves a trifluoromethylthiolation process and a radical 1,4-aryl migration from oxygen to carbon. The reaction shows excellent conversion of aryl propynyl ethers into trifluoromethyl-containing α,β-unsaturated aldehydes through a radical pathway. (Figure presented.).

Indium-catalyzed intramolecular hydroarylation of aryl propargyl ethers

Indium(iii) halides catalyze efficiently the intramolecular hydroarylation (IMHA) of aryl propargyl ethers. The reaction proceeds regioselectively with terminal and internal alkynes bearing electron-rich and electron-deficient substituents in the benzenes

Gold versus silver catalyzed intramolecular hydroarylation reactions of [(3-arylprop-2-ynyl)oxy]benzene derivatives

The scope and the generality of gold versus silver catalyzed intramolecular hydroarylation reactions of 3-[(3-arylprop-2-ynyl)oxy]benzene derivatives in terms of rings substitution were investigated. Only products deriving from 6-endo cyclization were exc

A simple and efficient one-pot synthesis of substituted benzo[b]furans by sonogashira coupling-5-endo-dig cyclization catalyzed by palladium nanoparticles in water under ligand- and copper-free aerobic conditions

A simple and efficient procedure for the synthesis of 2-substituted benzo[b]furan derivatives has been developed by the reaction of 2-iodophenols and arylacetylenes in water catalyzed by palladium nanoparticles generated in situ in open air. The reaction does not require any additive, ligand, or co-catalyst. The reaction occurs through Sonogashira coupling of 2-iodophenols with phenylacetylenes followed by 5-endo-dig cyclization. A series of functionalized benzo[b]furan derivatives was obtained in high yields by this procedure. A simple and efficient procedure for the synthesis of 2-substituted benzo[b]furan derivatives has been developed by the reaction of 2-iodophenols and arylacetylenes in water catalyzed by palladium nanoparticles generated in situ in open air.

Paradoxes in thermal stability of the liquid-crystal phase of phenylpropargyl phenyl ethers: I. Synthesis and mesogenic properties of phenylpropargyl phenyl ethers

The ethers PhC≡CCH2OC6H3RR′ were prepared in 51-83% yields by reactions of phenylpropargyl tosylate in alkaline solution with appropriate p- and o-substituted phenols. Below are given R, R′, and the ranges of existence of