930276-98-5Relevant academic research and scientific papers
Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition of nucleophiles to divinyl ketones
Silvanus, Andrew C.,Groombridge, Benjamin J.,Andrews, Benjamin I.,Kociok-Koehn, Gabriele,Carbery, David R.
supporting information; experimental part, p. 7491 - 7493 (2010/12/30)
Functionalized cyclohexanones are formed in excellent yield and diastereoselectivity from a phase transfer catalyzed double addition of active methylene pronucleophiles to nonsymmetrical divinyl ketones.
Asymmetric Ni-catalyzed conjugate allylation of activated enones
Sieber, Joshua D.,Morken, James P.
, p. 4978 - 4983 (2008/09/20)
The nickel-catalyzed enantioselective addition of allylboronic acid pinacol ester, allylB(pin), is described. This reaction is highly effective with dialkylidene ketones and favors the allylation of the benzylidene site in nonsymmetric substrates. The rea
Catalytic conjugate addition of allyl groups to styryl-activated enones
Sieber, Joshua D.,Liu, Shubin,Morken, James P.
, p. 2214 - 2215 (2007/10/03)
Conjugate addition of pinacolato(allyl)boron to benzylidenealkylidene ketones is remarkably facile when catalyzed by Ni(0) and Pd(0) complexes. Simple enones are inert to the reaction conditions, suggesting a significant activating effect by the auxiliary benzylidene unit. A comparison of different catalysts and substrates is provided, as is a mechanistic rationale, and an example of asymmetric catalysis. Copyright
