930601-46-0Relevant academic research and scientific papers
Carboxylated, heteroaryl-substituted chalcones as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases
Meng, Charles Q.,Ni, Liming,Worsencroft, Kimberly J.,Ye, Zhihong,Weingarten, M. David,Simpson, Jacob E.,Skudlarek, Jason W.,Marino, Elaine M.,Suen, Ki-Ling,Kunsch, Charles,Souder, Amy,Howard, Randy B.,Sundell, Cynthia L.,Wasserman, Martin A.,Sikorski, James A.
, p. 1304 - 1315 (2008/02/02)
Starting from a simple chalcone template, structure-activity relationship (SAR) studies led to a series of carboxylated, heteroaryl-substituted chalcone derivatives as novel, potent inhibitors of vascular cell adhesion molecule-1 (VCAM-1) expression. Corr
