93065-42-0

Upstream product

• 91-56-5 indole-2,3-dione 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 93065-27-1 N-[2-(7-Methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-phenyl]-4-nitro-benzamide 
• 1446212-87-8 phenylglyoxylic acid 
• 16063-05-1 2-(4-nitrophenyl)-4H-3,1-benzoxazin-4-one 
• 128672-01-5 (3-Mercapto-[1,2,4]triazino[5,6-b]indol-5-yl)-(4-nitro-phenyl)-methanone 
• 128649-55-8 9-hydroxyimino-2-imino-4-(p-nitrophenyl)<1,3,5>triazino<5,4-a>indole 
• 128649-54-7 1-(4-Nitro-benzoyl)-1H-indole-2,3-dione 3-oxime 
• 128649-52-5 (2-Imino-2H-imidazo[4,5-b]indol-4-yl)-(4-nitro-phenyl)-methanone 
• 128649-53-6 2-Imino-4-(4-nitro-phenyl)-2H-[1,3,5]triazino[1,2-a]indol-10-one 

Relevant academic research and scientific papers

Silver-Mediated Synthesis of 4H-Benzoxazin-4-ones by Intramolecular Decarboxylative O-Acylation Reactions with α-Oxocarboxylic Acid

The first example of an intramolecular decarboxylative acylation reaction for the synthesis of 4H-benzoxazin-4-one derivatives has been described. The silver-mediated reaction has a broad substrate scope and provides a mild and rapid approach to the corre

N-aroylated isatins: Antiglycation activity

A series of N-aroylated isatins 1-15 was synthesized and evaluated for their antiglycation activity. All compounds showed a varying degree of glycation inhibitory activity with IC50 values between 18.01 ± 0.05-693.7 ± 3.0 μM, when compared with the standard (aminoguanidine) having an IC50 = 268.7 ± 12.4 μM. Compound 1 was found to be the most active member of this series with an IC50 = 18.01 ± 0.05 μM. Compound 10 showed an IC50 = 72.5 ± 0.09 μM, whereas compound 7 has an IC50 = 80.18 ± 0.07 μM. Compounds 3, 9, and 13 showed IC50 values 170.2 ± 0.62, 117.91 ± 2.9, 171.3 ± 0.79 μM, respectively. Rest of the compounds along with parent isatin were found to be inactive. The structures of all the synthetic compounds were deduced by spectroscopic analysis.