93075-10-6Relevant academic research and scientific papers
Direct N3 Alkylation of Uracil and Derivatives via N1-[2-(trimethylsilyl)ethoxymethyl] Protection
Arias,Guzmán,Jaime-Figueroa,Lopez,Morgans Jr.,Padilla,Pérez-Medrano,Quintero,Romero,Sandoval
, p. 1233 - 1234 (2007/10/03)
Protection at N1 position of uracil and uracil analogs as 2-(trimethylsilyl)ethoxymethyl derivatives permits the clean alkylation at N3. These protected uracils are quite stable in a wide range of pH.
A FACILE CONVERSION OF 5-TRIFLUOROMETHYL-5,6-DIHYDROURACILS TO 5-TRIFLUOROMETHYLURACILS
Fuchikami, Takamasa,Yamanouchi, Akiko
, p. 1595 - 1598 (2007/10/02)
5-Trifliuoromethyl-5,6-dihydrouracils were directly converted to the corresponding 5-trifluoromethyluracils by the reaction with copper(II) bromide in dimethylformamide/water or dimethylformamide/acetic acid in good to excellent yields.
