930769-46-3 Usage
Uses
Used in Pharmaceutical Industry:
4-(4-Fluorophenyl)-2-azetidinone is used as a precursor in the synthesis of new drugs and medications for its potential to exhibit biological activities such as antibacterial, antifungal, and antiviral properties. The presence of the azetidinone ring and the fluorophenyl group allows for the development of compounds with enhanced pharmacological properties and specificity towards certain targets.
Used in Medicinal Chemistry Research:
4-(4-Fluorophenyl)-2-azetidinone serves as a valuable compound in medicinal chemistry research, where its unique structure and potential therapeutic applications are explored. Researchers can investigate its interactions with various biological targets and pathways, potentially leading to the discovery of novel drugs with improved efficacy and selectivity.
Used in Drug Discovery:
In the field of drug discovery, 4-(4-Fluorophenyl)-2-azetidinone is utilized for its potential to contribute to the development of innovative therapeutic agents. Its unique chemical structure and biological activities make it a promising candidate for further optimization and modification to enhance its pharmacological profile and therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 930769-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,0,7,6 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 930769-46:
(8*9)+(7*3)+(6*0)+(5*7)+(4*6)+(3*9)+(2*4)+(1*6)=193
193 % 10 = 3
So 930769-46-3 is a valid CAS Registry Number.
930769-46-3Relevant academic research and scientific papers
The acid-mediated ring opening reactions of α-aryl-lactams
King, Frank D.,Caddick, Stephen
experimental part, p. 3244 - 3252 (2012/06/01)
4-Aryl-azetidin-2-ones (β-lactams) undergo ring opening with triflic acid to give cinnamamides which, in benzene, react further to give 3-aryl-3-phenyl-propionamides. Prolonged reaction times in benzene give 3,3-diphenyl-propionamide via an aryl/phenyl ex
A new route to enantiopure β-aryl-substituted β-amino acids and 4-aryl-substituted β-lactams through lipase-catalyzed enantioselective ring cleavage of β-lactams
Forro, Eniko,Paal, Tihamer,Tasnadi, Gabor,Fueloep, Ferenc
, p. 917 - 923 (2007/10/03)
A simple and efficient direct enzymatic method was developed for the synthesis of 4-aryl-substituted β-lactams and the corresponding β-amino acid enantiomers through the CAL-B (lipase B from Candida antarctica)-catalyzed enantioselective (E > 200) ring cleavage of the corresponding racemic β-lactams with 1 equiv. of H2O in i-Pr2O at 60°C. The product (R)-β-amino acids (ee ≥ 98%, yields ≥ 42%) and unreacted (S)-β-lactams (ee ≥ 95%, yields ≥ 41%) could be easily separated. The ring opening of enantiomeric β-lactams with 18% HCl afforded the corresponding enantiopure β-amino acid hydrochlorides (ee ≥ 99%).
