930785-40-3

Basic information

• Product Name: TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE
• Synonyms: TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE;9-Boc-1-Oxa-4,9-diazaspiro[5.5]undecane;1-Oxa-4,9-diazaspiro[5.5]undecane-9-carboxylic acid, 1,1-diMethylethyl ester;1-Oxa-4,9-diaza-spiro[5.5]undecane-9-carboxylic acid tert-butyl ester;1-Oxa-4,9-diazaspiro[5.5]undecane,N9-BOCprotected;EOS-62238
• CAS NO: 930785-40-3
• Molecular Formula: C₁₃H₂₄N₂O₃
• Molecular Weight: 256.34
• Mol File: 930785-40-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 364.211 °C at 760 mmHg
• Flash Point: 174.069 °C
• Appearance: /
• Density: 1.11
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.514
• Storage Temp.: 2-8°C
• PKA: 8.82±0.20(Predicted)
• CAS DataBase Reference: TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE(930785-40-3)
• EPA Substance Registry System: TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE(930785-40-3)

Safety Data

• Hazardous Substances Data: 930785-40-3(Hazardous Substances Data)

Usage

General Description

Tert-butyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate is a chemical compound with a highly complex and specific molecular structure. It is commonly used in pharmaceutical research and development as a synthetic intermediate in the creation of unique drug compounds. This chemical is known for its spirocyclic structure and its potential application in drug discovery and medicinal chemistry. Furthermore, it has the potential to exhibit various pharmacological activities due to its unique molecular architecture, and its synthesis and characterization are of particular interest to researchers in the pharmaceutical industry.

InChI:InChI=1/C13H24N2O3/c1-12(2,3)18-11(16)15-7-4-13(5-8-15)10-14-6-9-17-13/h14H,4-10H2,1-3H3

Upstream product

• 1097920-69-8 4-benzyl 9-tert-butyl 1-oxa-4,9-diazaspiro[5.5]undecane-4,9-dicarboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 41661-47-6 piperidin-4-one 
• 819800-93-6 tert-butyl 4-hydroxy-4-(nitromethyl)-piperidine-1-carboxylate 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 147804-30-6 1-oxa-6-aza-spiro-[2.5]octane-6-caboxylic acid tert-butyl ester 
• 392331-66-7 4-aminomethyl-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester 
• 1160247-07-3 tert-butyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate 

Downstream Products

• 1097920-69-8 4-benzyl 9-tert-butyl 1-oxa-4,9-diazaspiro[5.5]undecane-4,9-dicarboxylate 
• 1352926-03-4 tert-butyl 4-benzyl-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate 
• 930785-39-0 tert-butyl 4-{2-[3-(2-methoxy-2-oxoethyl)phenoxy]ethyl}-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate 

Relevant articles and documents

COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR

This disclosure pertains to compounds, the preparation thereof, and the use of these compounds in the treatment of prostate cancer, including metastatic and/or castrate-resistant prostate cancer, in subjects in need thereof.

1,1,1-TRIFLUORO-3-HYDROXYPROPAN-2-YL CARBAMATE DERIVATIVES AND 1,1,1-TRIFLUORO-4-HYDROXYBUTAN-2-YL CARBAMATE DERIVATIVES AS MAGL INHIBITORS

The present invention provides, in part, compounds of Formula I and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

The present invention provides compounds of Formula I (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.