930797-38-9Relevant academic research and scientific papers
Radiosynthesis of new carbon-11-labeled nimesulide analogs as potential PET SAER tracers for imaging of aromatase expression in breast cancer
Wang, Min,Gao, Mingzhang,Miller, Kathy D.,Sledge, George W.,Hutchins, Gary D.,Zheng, Qi-Huang
scheme or table, p. 749 - 758 (2011/02/27)
Carbon-11-labeled nimesulide analogs, N-[11C]methyl-N-(2- benzyloxy-4-nitrophenyl)methanesulfonamide ([11C]4a), N-[ 11C]methyl-N-[2-(4'-methylbenzyloxy)-4-nitrophenyl] methanesulfonamide ([11C]4b), N-[11/s
Synthesis and biological evaluation of selective aromatase expression regulators in breast cancer cells
Su, Bin,Landini, Serena,Davis, Danyetta D.,Brueggemeier, Robert W.
, p. 1635 - 1644 (2007/10/03)
Aromatase converts androgens to estrogens and is a particularly attractive target in the treatment of estrogen receptor positive breast cancer. The enzyme is encoded by the CYP19 gene, which is expressed in a tissue-specific manner. Prostaglandin E2
SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS
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, (2010/11/28)
Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloakyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alk
