930798-41-7

Upstream product

• 877995-77-2 1-(4-bromophenoxy)-2-(2,6-dichloro-4-methylphenoxy)ethane 
• 106-41-2 4-bromo-phenol 
• 34743-88-9 2-(4-bromophenoxy)ethanol 

Downstream Products

• 930798-43-9 (3R,4S)-1-benzyl-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}pyrrolidine-3-carboxylic acid cyclopropyl-(2,3-dimethylbenzyl)amide 
• 930798-42-8 (3R,4S)-1-benzyl-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}pyrrolidine-3-carboxylic acid 

Relevant academic research and scientific papers

PYRROLIDINE-3-CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF RENIN

The invention relates to novel pyrrolidine-3-carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these novel compounds, pharmaceutical compositions comprising such compounds and especially the use of such compounds as inhibitors of renin.