93138-07-9

Basic information

• Product Name: N-(3-nitrophenyl)benzo[d]thiazol-2-amine
• Synonyms: N-(3-nitrophenyl)benzo[d]thiazol-2-amine
• CAS NO: 93138-07-9
• Molecular Weight: 271.299
• Mol File: 93138-07-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(3-nitrophenyl)benzo[d]thiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-nitrophenyl)benzo[d]thiazol-2-amine(93138-07-9)
• EPA Substance Registry System: N-(3-nitrophenyl)benzo[d]thiazol-2-amine(93138-07-9)

Safety Data

• Hazardous Substances Data: 93138-07-9(Hazardous Substances Data)

Upstream product

• 13140-66-4 1-(3-nitrophenyl)-3-phenylthiourea 
• 75-15-0 carbon disulfide 
• 137-07-5 2-amino-benzenethiol 
• 99-09-2 3-nitro-aniline 
• 893005-72-6 C₁₃H₁₀BrN₃O₂S 
• 13037-60-0 1-bromo-2-isothiocyanatobenzene 

Relevant articles and documents

N-Iodosuccinimide mediated intramolecular oxidative C(sp 2)-S bond formation for the synthesis of 2-aminobenzothiazole derivatives

An extremely efficient synthetic method for the preparation of 2-aminobenzothiazole derivatives starting from arylthioureas by using N-iodosuccinimide has been reported. This protocol features a mild reaction conditions, a short reaction time, and metal-free oxidative conditions for C (sp 2)-S bond construction.

An "on-water" exploration of CuO nanoparticle catalysed synthesis of 2-aminobenzothiazoles

An "on-water" one-pot process has been engineered for the preparation of 2-aminobenzothiazole from ortho-halo (-F, -Cl, -Br and -I) substituted unsymmetrical thioureas. For ortho -I and -Br substrates the reactions afford 2-aminobenzothiazoles under metal free condition promoted by base. However, the relatively inert ortho -Cl and -F substrates undergo intramolecular arylthiolation only in the presence of CuO nanoparticles yielding 2-aminobenzothiazoles. This methodology provides easy access to aminobenzothiazoles utilising even the ortho -Cl and -F substrates. The catalyst is recyclable several times without loss of substantial activity. Other remarkable features include the wide range of functional group tolerance, absence of chromatographic purification (for ortho -I and -Br substrates) and providing moderate to excellent yield of the products under mild conditions, thus rendering the methodology as a highly eco-friendly alternative to the existing methods.