931402-28-7

Upstream product

• 908093-98-1 diazodiphenylmethane 
• 86386-65-4 1-[(4-fluorophenyl)methyl]-2,5-pyrrolidinedione 
• 871470-94-9 7-(4-fluoro-benzyl)-5,9-dihydroxy-3-methoxy-pyrrolo[3,4-g]quinoline-6,8-dione 
• 907205-59-8 carbonic acid ethyl ester 7-(4-fluoro-benzyl)-3,5-dimethoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester 
• 907205-57-6 carbonic acid ethyl ester 7-(4-fluoro-benzyl)-5-hydroxy-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester 
• 907205-56-5 carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of novel tricyclic HIV-1 integrase inhibitors by modification of its pyridine ring

This communication details both the syntheses and biological evaluation of a novel class of HIV-1 integrase inhibitors. When the quinoline moiety is replaced with the quinoxoline moiety, the antiviral activity is significantly compromised. Similarly, intr