871470-94-9Relevant articles and documents
Design, synthesis, and biological evaluation of novel tricyclic HIV-1 integrase inhibitors by modification of its pyridine ring
Metobo, Sammy E.,Jin, Haolun,Tsiang, Manuel,Kim, Choung U.
, p. 3985 - 3988 (2007/10/03)
This communication details both the syntheses and biological evaluation of a novel class of HIV-1 integrase inhibitors. When the quinoline moiety is replaced with the quinoxoline moiety, the antiviral activity is significantly compromised. Similarly, intr