931405-92-4

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 938-94-3 (R,S)-2-(4'-methylphenyl) propionic acid 

Downstream Products

• 1169704-46-4 C₁₉H₁₉NO₂S 
• 1308659-00-8 C₁₉H₁₉NO₃ 
• 93862-56-7 (S)-4-Isopropyl-3-((R)-2-p-tolyl-propionyl)-oxazolidin-2-one 
• 93862-56-7 (S)-4-Isopropyl-3-((S)-2-p-tolyl-propionyl)-oxazolidin-2-one 
• 1308658-89-0 C₁₆H₁₉NO₅ 
• 1308658-90-3 C₁₆H₁₉NO₅ 

Relevant academic research and scientific papers

Efficient parallel resolution of pentafluorophenyl active esters using quasi-enantiomeric combinations of oxazolidin-2-ones

The parallel resolution of racemic pentafluorophenyl 2-aryl/ phenylpropanoates and butanoates using an equimolar combination of quasi-enantiomeric Evans oxazolidin-2-ones is discussed. The levels of diastereoselectivity were excellent (>90% de) leading to separable quasi-enantiomeric oxazolidin-2-ones in good yield. This methodology was used to resolve a series of structurally related 2-aryl/phenylpropanoic and butanoic acids.

Synthesis, characterisation and application of enantiomeric isotopomers of Evans' oxazolidinones

The synthesis of a series of enantiomerically pure deuterium-labelled isotopomeric Evans' oxazolidinones is discussed.